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CASE REPORT
Year : 2021  |  Volume : 8  |  Issue : 1  |  Page : 3

Treatment of membranoproliferative glomerulonephritis with traditional chinese medicine and rituximab: A case report


1 Department of Nephrology, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing, China
2 Department of Nephrology, Xiyuan Hospital of China Academy of Chinese Medical Sciences; Department of clinical medicine, Graduate School of Beijing University of Chinese Medicine, Beijing, China

Correspondence Address:
Dr. Ren-huan Yu
Department of Nephrology, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Xiyuan Cao Chang, Haidian, Beijing 100091
China
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/imna.imna_10_21

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Membranoproliferative glomerulonephritis (MPGN) is usually characterized by refractory nephrotic syndrome and is associated with a poor prognosis. An older patient diagnosed with MPGN had a 20-year history of proteinuria and had clinical manifestations of nephrotic syndrome in the past 2 years. MPGN. Before the patients received an 11-month traditional Chinese medicine (TCM) treatment, the patient was treated with prednisone, tacrolimus, mycophenolate mofetil, and rituximab for 11 months. After 22 months, the urine protein level decreased to <1 g/d, with normal plasma albumin level, and remarkably increased glomerular filtration rate. Combination of TCM with Western medicine for 22 months was effective for the treatment of MPGN.


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